Master's Thesis · Computational Science

Using probabilistic methods for hierarchical visualization of single-cell RNA-seq data

Master's thesis by Tobias J. Beers at the University of Amsterdam (Computational Science, 2020). The work focuses on probabilistic, hierarchical visualisations of high-dimensional single-cell RNA-seq data to uncover structure in cell populations.

Thesis details

This thesis investigates probabilistic methods for building hierarchical visualisations of single-cell RNA-seq data. Rather than relying on a single low-dimensional embedding, the work looks at layered structures that can reveal relationships between cell types and subpopulations. The aim is to provide interpretable overviews that remain faithful to the underlying uncertainties in the data.

Author Tobias J. Beers
Institution University of Amsterdam — Computational Science
Year 2020
Single-cell RNA-seq Hierarchical visualization Probabilistic methods Computational biology Complex systems
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